Presented for your consideration: The Death of Death?

Who wants to live to be 1,000?

If you wish to be a prophet, first you must dress the part. No more silk ties or tasseled loafers. Instead, throw on a wrinkled T-shirt, frayed jeans, and dirty sneakers. You should appear somewhat unkempt, as if combs and showers were only for the unenlightened. When you encounter critics, as all prophets do, dismiss them as idiots. Make sure to pepper your conversation with grandiose predictions and remind others of your genius often, lest they forget. Oh, and if possible, grow a very long beard.

By these measures, Aubrey de Grey is indeed a prophet. The 42-year-old English biogerontologist has made his name by claiming that some people alive right now could live for 1,000 years or longer. Maybe much longer. Growing old is not, in his view, an inevitable consequence of the human condition; rather, it is the result of accumulated damage at the cellular and molecular levels that medical advances will soon be able to prevent — or even reverse — allowing people to go on living pretty much indefinitely. We'll still have to worry about angry bears and falling pianos, but aging, the biggest killer of all, will cease to be a threat. Death, as we know it, will die.

Mainstream gerontologists do not agree and hate to even raise the topic in public. They shy away from talk about life extension or "curing" aging and prefer to focus on keeping older people healthy for as long as possible, a goal referred to in the discipline as "compression of morbidity" or "healthspan." Many of them write off Mr. de Grey as more beard than brain.

So ... is he crazy? Not in the sense that he is divorced from reality or just making things up as he goes along. Mr. de Grey is a serious, thoughtful, sincere, prolific, even brilliant researcher and thinker who seems to have devoted every last ounce of his intellect to conquering the single biggest medical menace facing mankind. Along the way, he has acquired plenty of supporters and detractors — and gained the respect of some of the top scientists in the world.

He even has a plan. It is, to say the least, ambitious, and it depends on a number of techniques and treatments that have yet to be developed (curing cancer, for instance, is one of the steps). His approach, which he has dubbed Strategies for Engineered Negligible Senescence, draws from different branches of science and medicine and is enough to spin the heads of specialists and nonspecialists alike. It has also caused a stir, something Mr. de Grey certainly knows how to do. "One hundred and fifty thousand people die every day, and two-thirds of those die of aging in one way or the other," he says, while nursing a pint of fine English ale. "If I speed up the cure for aging by one day, then I've saved 100,000 people." He pauses thoughtfully for a moment. "Actually, I probably do that every week."
(Thanks to The Chronicle and Drudge for the heads up.)